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Upon addition of ME, the olefinic proton (H a ) of TPE-DCV with chemical shift of ~8.4 ppm disappears and a new peak (H b ) at 4.69 ppm arises, suggestive of the addition reaction of thiol on the vinyl group (Figure S6) 58

In a murine study, it was shown that the administration of vitamins C and E caused decreases in ragweed extract-induced ROS levels and is associated with lower airway allergic inflammation [82]

Conversely, [U- 13 C]glucose tracing showed GGCT overexpression enhanced Glc-derived carbon flux into the TCA cycle (increased m + 2 labeling of succinate, fumarate, malate), which was reversed by the E98A mutant (Fig