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It calls this the mechanistic advantage over GLP-1-only agents
Severe freezing damage can cause visible cloudiness, particles, or color changes
Embodiment 23: The process according to Embodiment 22, wherein the fluorinated alcohol is selected from the group consisting of 2,2,2-trifluoroethanol (TFE), 1,1,1,3,3,3-hexafluoro-2-propanol (HFIP), 2,2,3,3-tetrafluoro-1-propanol, 2,2,3,3,3-pentafluoro-1-propanol, pentafluorophenol, nonafluoro-tert-butyl alcohol, 3,3,4,4,4-pentafluoro-1-butanol, 4,4,5,5,5-pentafluoro-1-pentanol, 2,2,3,4,4,4-hexafluoro-1-butanol, 1,1,1,3,3,3-hexafluoro-2-methyl-2-propanol, 1,1,1,3,3,3-hexafluoro-2-phenyl-2-propanol, and mixtures thereof
unspecified in the record, 32 (11.1 percent)
In rare cases, serious regurgitant cardiac valvular disease has occurred
