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Dual agonism at the amylin receptor (a heterodimer of calcitonin receptor + RAMP1/2/3) and the calcitonin receptor in area postrema and arcuate nucleus, reducing food intake and promoting satiety
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pathway: a novel target for cancer therapy
Many teams also build in a washout period at the end of a study before any follow-up dosing phase, giving the GH axis time to return to baseline and reducing the risk of carryover effects confounding a subsequent phase
F.Santos Duarte LanaA
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