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In terms of treatments, epigenetic therapy, including treatment with DNA methyltransferase and histone deacetylase inhibitors (DNMTis and HDACis, respectively), can increase the numbers of CD45 + immune cells, active CD8 + T cells and NK cells in the TME, reducing immunosuppression and the tumor burden through activation of type I interferon signaling in murine ovarian cancer [171, 172]

Fucoidan from Sargassum hemiphyllum inhibits infection and inflammation of Helicobacter pylori

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