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Market Ozempic and Rybelsus (oral semaglutide) have proven to be blockbusters for Novo Nordisk, with Ozempic being the companys top selling drug in 2021 with global sales reaching over 33 billion kroner or just over $4.5 billion

However, clinical evidence demonstrating that reshaping the axis independently of weight change remains scarce

Diabetes 61 , 29932997 (2012)

B12 may further support this process by promoting the proper functioning of insulin-producing cells in the pancreas

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