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Neutrophil extracellular traps (NETs) are comprised of modified neutrophilic chromatin that is expelled into the system to neutralize and prevent the dissemination of microbes, whilst concurrently alerting the immune system of the infection [25,26,27]
It is a synthetic fragment of a protein found naturally in gastric juice, and the interest centers on its apparent role in tissue repair signaling
It plays a crucial role in detoxification, immune function, and protection against oxidative stress
Chronic CLE tends to follow a chronic relapsing course for years, with flares in spring and summer, and resolution with scarring if untreated