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The regulation of COX2 expression is complex, involving transcriptional and post-transcriptional mechanisms influenced by cytokines, growth factors, and pro-inflammatory stimuli (225)

Neuroscience 16(4):859863 Martin V, Sainz RM, Mayo JC, Antolin I, Herrera F, Rodriguez C (2003) Daily rhythm of gene expression in rat superoxide dismutases

This allows for efficient absorption and delivery to the bloodstream, where it can interact with the pituitary gland and stimulate GH release