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La comunidad cientfica reclama estudios independientes de alta calidad metodolgica antes de considerar avance a fase clnica humana formal

Proximal gastrectomy is associated with a lower incidence of anemia and vitamin B12 deficiency compared to total gastrectomy in patients with upper gastric cancer (233)

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Those with naturally high NNMT activity might respond more dramatically to inhibition, while those with lower baseline activity might see more modest effects

(1999) Supplementation with vitamin B12 decreases homocysteine and methylmalonic acid but also serum folate in patients with end-stage renal disease