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Some individuals, including those with a history of pancreatitis, medullary thyroid cancer, or severe gastrointestinal disorders, should weigh risks and benefits with their healthcare provider
The GLP-1 analogs liraglutide and semaglutide reduce atherosclerosis in ApoE / and LDLr / mice by a mechanism that includes inflammatory pathways
others are more limited
In vivo preclinical models investigating glucose regulation, body weight, cardiovascular parameters, and inflammatory responses through GLP-1R pathways, hypothalamic signaling, and cytokine modulation
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