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Most are approved for patients with a body mass index above a specific cutoff, often 27 or 30, especially when other health problems, such as diabetes or heart disease, are present

For diabetes management, these medications improve glycemic control by enhancing glucose-dependent insulin secretion, suppressing inappropriate glucagon release, and slowing gastric emptying

Doroszewska K, Milewicz T, Mroziska S, Janeczko J, Rokicki R, Janeczko M, Warzecha D, Marianowski P (2019) Blood pressure in postmenopausal women with a history of polycystic ovary syndrome

It explains how a decline or imbalance in estradiol levels affects insulin sensitivity in the brain