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Mounjaros nausea rates are lower than Wegovy 2.4mg despite producing greater weight loss likely due to the GIP mechanism partially counterbalancing GLP-1s GI effects
Are there any other medications or lifestyle choices I should make while tapering off semaglutide
Effects on insulin resistance and lipotoxicity GLP-1 RAs target several fundamental mechanisms in NASH pathogenesis
Efficacy estimand: This analysis was not included in the statistical testing hierarchy, and as such, is hypothetical and was not controlled for multiplicity Study design OASIS 4 7,10 : A randomized, double-blind, placebo-controlled 64-week trial of 307 adults with obesity (BMI 30 kg/m) or overweight (BMI 27 kg/m-29.9 kg/m) and 1 weight-related comorbid condition, such as treated or untreated dyslipidemia or hypertension
An individualised riskbenefit discussion with a specialist is appropriate for anyone in this group who may be considered for treatment in future
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