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This contributes to resistance to gemcitabine in patients with PDAC [115]
& Eisbach, K
Research demonstrates that BPC-157 upregulates VEGFR2 at both mRNA and protein levels in vascular endothelial cells without increasing VEGF-A itself, effectively sensitizing cells to existing VEGF in the tissue microenvironment rather than simply adding more growth factor signal
This process is called glutathione conjugation
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