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Despite the use of rodents and small mammals being commonplace in research, in particular for the development of novel therapeutic agents, caution still needs to be practiced when extrapolating research data to clinical applications
Combining tesofensine with stimulants (DMAA, ephedrine) or serotonergic compounds (SSRIs, MAO inhibitors) significantly increases cardiovascular events and serotonin syndrome risk
Brill KJ, Li Q, Larkin R, Canaday DH, Kaplan DR, Boom WH, et al
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Effect of continued weekly subcutaneous semaglutide vs placebo on weight loss maintenance in adults with overweight or obesity: the STEP 4 randomized clinical trial
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