The Journal of clinical investigation 83 , 12471252, doi: 10.1172/JCI114008 (1989)
Different strategies were used to improve the peptide half-life including sequence modifications (exenatide, lixisenatide) 36,37 , conjugation to molecules with propensity to bind albumin (liraglutide, semaglutide) 36,37 , fusion to large proteins (albiglutide, dulaglutide, efpeglenatide) 36,37 , side chain cross linking 38,39 , and -residue replacement 40,41,42 (Fig
Q2: What is the shelf life
From what I can see, iCare is a U.S.-based private label skincare company with a strong focus on facial care products rather than trying to be everything to everyone
The reasons are specific and addressable when identified early in the protocol