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15 GSSG is unable to perform antioxidant functions but can be converted back to rGSH by glutathione reductase (GSR), 15,17,18 which requires the oxidation of NADPH to NADP+
It is possible that the supplements did not triggercancer but rather accelerated the progression of existing undiagnosed cancers, making later discovery of the disease likely.In other words, it could be that while antioxidants might prevent DNA damageand thus impede tumor initiationonce a tumor is established, antioxidants might facilitate the malignant behavior of cancer cells, Schafer says
Improved Mood and Mental Clarity: The combination of B vitamins, magnesium, and the neuro-protective effects of Glutathione can help to reduce stress, alleviate symptoms of anxiety and depression, and banish brain fog, leading to improved focus and a greater sense of well-being
More importantly, an oxidative state promotes protein glutathionylation (S-S disulphide binding of glutathione to a cysteine residue)