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[29] Chemical reactions [edit] In the cobalamins, cobalt normally exists in the trivalent state, Co(III)

Weeks 26: The correction window for the underlying deficiency itself, not just symptoms

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None of these pharmacological actions directly involve vitamin B12 metabolism or supplementation

Interestingly, greater benefits were seen in those with high compared to low homocysteine concentrations at baseline, suggesting the importance of lowering homocysteine levels in prevention of brain atrophy and cognitive decline (91-93)