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IP teams should integrate post-LOE formulary defense strategy into biologic lifecycle planning at NDA/BLA submission, not at patent expiration
Regarding gastrointestinal symptoms, even something as simple as switching the time of dosing from morning to bedtime can be helpful, Garvey noted
The CD44v9/xCT pathway inhibitor may provide a therapeutic option for treating certain cancers (Table IV)
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Phentermine follows a similar pattern of regain, though the data is less precisely quantified because the shorter treatment duration and older study designs make direct comparisons difficult
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