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Erythema Nodosum las clulas beta pancreticas Liberacin de insulina Farmacocintica Absorcin: Rpida Inicio de accin ms rpido que las sulfonilureas Distribucin: Ampliamente unidas a protenas Duracin de accin ms corta que las sulfonilureas Metabolismo: Heptico A travs del sistema de citocromo P450: CYP3A4 CYP3A4 Class 3 Antiarrhythmic Drugs (Potassium Channel Blockers) CYP2C8 CYP2C8 A liver microsomal cytochrome p450 hydroxylase that oxidizes a broad spectrum of substrates including steroids, fatty acids, and xenobiotics

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Additionally, adequate levels of vitamins C, B6, and niacin are necessary cofactors for the enzymatic reactions

While these injections are generally well tolerated, there are certain gastrointestinal side effects that may occur, such as vomiting, diarrhea, and nausea

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