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Nevertheless, if drugs inhibit ThDP-dependent enzymes, as, e.g., omeprazole does (157), direct exposure of the gastrointestinal system to oral drugs may increase its vulnerability compared to other tissues

Bruguera et al

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Comprehensive Screening Protocols Prior to initiating treatment with BPC-157 or TB-500, healthcare professionals should conduct a comprehensive cancer risk assessment and screening protocol tailored to each patients individual risk profile

In addition, SASP can promote a pro-tumorigenic microenvironment, inducing malignant characteristics in neighboring cells and supporting tumor growth