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Measurements included hydrodynamic diameter (2RH), polydispersity index (PDI) and zeta potential (ZP) (Table 1), which were obtained using dynamic light scattering (DLS) with a NanoBrook Omni analyzer (Brookhaven Instruments Corporation, Holtsville, NY, USA)
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The dependence of tyrosine hydroxylase on BH 4 necessitates the coupling to the action of dihydropteridine reductase (encoded by the QDPR gene: quinoid dihydropteridine reductase) as is the situation for tryptophan hydroxylase (see below) and phenylalanine hydroxylase
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