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Sublingual troches: Typical dose: 50-200mcg per troche Frequency: 1-2 times daily Administration: Dissolve between cheek and gum for 15-20 minutes Absorption: Bypasses first-pass liver metabolism through oral mucosa Liposomal oral: Typical dose: 100-500mcg Frequency: Once daily Note: Lipid encapsulation protects peptide through digestion Oral forms suit those unwilling to inject who still want systemic rather than purely local effects

By contrast, reducing intra-BNST levels of ALLO in females, who have higher brain ALLO levels at baseline, enhances the expression of contextual freezing (239)

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Without explaining why timing creates mechanistic differences

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