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The functional conservation of both GSTs and SULTs across species highlights their evolutionary significance in cellular detoxification and stress regulation, which are essential for maintaining homeostasis and preventing cellular damage 52

Moreover, treatment with antioxidants and ROS scavengers can sustainably reduce blood pressure in many experimental models of hypertension [245]

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Sex and stressor modality influence acute stress-induced dynamic changes in corticolimbic endocannabinoid levels in adult Sprague Dawley rats