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Lighten with age Dermoscopic features (hover over terminologies for description) Tend to be uniform or darker in the centre Grouped smooth-looking globules, sometimes giving a cobblestone appearance Bloods vessels are ''comma-like'' in shape (click on the link for an overview of dermoscopic vessel patterns) In older people lesions may be relatively banal and show little remaining pigment As discussed in the chapter Melanoma - an overview the dermoscopic examination of melanocytic lesions requires considerable experience Clinical Images Please refer to notes on image rights at bottom of the page with regards to individual image ownership

Oxidative stress and the pathogenesis of neurodegenerative disorders