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2025 Sep 16;17(9):e92454
BrulsYMHOp den KampYJMPhielixELindeboomLHavekesBSchaartGet al
Although no significant differences in heart rate were found in the later stages of the test, the early-stage benefits suggest that LC might assist in maintaining cardiovascular efficiency during exercise, which could contribute to sustained performance in endurance athletes
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In a Phase 1 randomized, double-blind, placebo-controlled trial involving obese adults (NCT04478708), AMG 133 exhibited good safety and tolerability profiles and demonstrated significant dose-dependent weight loss effects
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