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51-53 Strengths and limitations To our knowledge, this is the first systematic review to comprehensively report on the trends of enrollment of females in GLP-RA RCTs

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Summary: Combination therapy with GLP-1 receptor agonists and SGLT2 inhibitors uses two distinct drug classes simultaneously to improve glycaemic control in type 2 diabetes through complementary mechanisms whilst providing cardiovascular and renal protection

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doi: 10.1038/s44319-025-00384-x 80 WestermeierFFismanEZ

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Drugs.com Because of this evolving science, clinics such as CutKilo are ideally placed to guide patients through safe, responsible use of these medications, and to manage the transition as new drugs become available

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One aspect of research that is needed is whether longer-term treatment with GLP-1 receptor agonists could rewire the bodys metabolic status such that people would be reprogrammed to maintain a different body weight, said Spatz

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