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In NSCLC, CHAC1 plays a crucial role in preserving mitochondrial respiratory function under conditions of cysteine starvation

[1] Symptoms may include frequent urination, trouble starting to urinate, weak stream, inability to urinate, or loss of bladder control

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Reactive astrogliosis in neuroinfection is thus defensive and neuroprotective: inhibition of astrocytic reactivity, for example by knocking out GFAP, 231 or by genetic deletion of NK-1R receptor for substance P, which suppresses reactive astrogliosis that defines resistance to N