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For example, there is a seven times greater risk of diabetes in obese people compared to those of healthy weight, with a three-fold increase in risk for overweight people[14]
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Animal studies show that these medications cause developmental abnormalities in the fetus
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However, using an ECD-binding antibody Fab fragment (Fab7F38) for co-crystallization, we successfully crystallized the GLP-1RPF-06372222Fab7F38 complex
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