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Higher doses may increase the risk of side effects, while underdosing may not provide the full therapeutic effects

However, the effect these drugs have on stomach emptying appears to at least partly explain why the oral contraceptive pill may not work as well as expected

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Quantification of the contribution of GLP-1 to mediating insulinotropic effects of DPP-4 inhibition with vildagliptin in healthy subjects and patients with type 2 diabetes using exendin [939] as a GLP-1 receptor antagonist