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Quality assessment was undertaken by two independent reviewers
N Engl J Med (2017) 376(24):236775
Genetic and environmental factors contribute to its formation
By reducing appetite, promoting feelings of fullness, and improving blood sugar control, GLP-1 medications can lead to significant weight loss in individuals with obesity or overweight conditions
Evidence-based levers that reliably move the needle: A sustainable calorie deficit with adequate protein Resistance training plus daily movement Sleep and stress management (often underestimated) Clinician-guided options when appropriate, including FDA-approved obesity medications (e.g., Wegovy and Zepbound ) and weight loss injections A good rule of thumb: don't outsource a fundamentals problem to an unproven tool
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