These genes were also activated by Pst DC3000 AvrRpm1 , suggesting that they might also play a role in defense against bacteria (Blanco et al., Ralstonia solanacearum is an important plant pathogenic, soil-borne bacterium, which causes the widespread bacterial wilt disease (Peeters et al., 2013)
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Weight-loss drugs have a history of tripping into mitochondrial liabilities (e.g., troglitazone)
Cell Metab 36(6):13021319 e12 Scott Butsch W, Sulo S, Chang AT, Kim JA, Kerr KW, Williams DR et al (2025) Nutritional deficiencies and muscle loss in adults with type 2 diabetes using GLP-1 receptor agonists: A retrospective observational study
They also observed less response to GLP-1 in the pancreas and in the gut of these mice, indicative of GLP-1 resistance, yet there was no change in the expression of GLP-1 receptors in these tissues