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Others feel fine initially but develop nausea, burping, reflux, or bloating later

Data extracted included study design, patient demographics, intervention details, outcomes, and adverse events

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Dietary supplements in the United States do not require FDA approval before they reach store shelves

Editorial Advisory Board Member, Harvard Health Publishing Some people who struggle with weight loss have been able to find assistance from several FDA-approved weight-loss medications, such as bupropion plus naltrexone (Contrave), phentermine (Adipex-P), phentermine plus topiramate (Qsymia), and orlistat (Xenical, Alli)