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BRCA1 gene promoter methylation status in high-grade serous ovarian cancer patients--a study of the tumour Bank ovarian cancer (TOC) and ovarian cancer diagnosis consortium (OVCAD)

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Age-Related Risk: One study conducted in a Russian population found that the breast cancer risk associated with the H63D pathogenic variant increased significantly in women over the age of 57 years, highlighting the importance of hormonal changes and iron accumulation over time

Wing, Rena R., et al