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The sequence influences the expression of Egr-1 genes involved in early wound healing phases

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note that daily dosing is only for the activation phase of the GLOW protocol (weeks 1-4) , decreasing to 5x per week for the remodeling phase (weeks 5-8), and further reduced to 2-3x per week during maintenance (weeks 9-12)

This response was more limited to the gut, so may have helped more in people with gastrointestinal issues like irritable bowel syndrome and Crohns