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With a vitamin b12 deficiency, dermatologic issues can arise such as hyperpigmentation and inflammation

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Baseline labs (B12, folate, metabolic panel, kidney function) are recommended before starting

For hematocrit and reticulocyte counts, recommendations are to repeat these tests daily from the 5th to 7th days of treatment and then frequently until the hematocrit returns to a normal range.[9][16][22] Both serum potassium concentrations and the platelet count need to be monitored carefully after parenteral administration of cyanocobalamin