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These comparisons underscore a clear mechanism- the more cohesive and opaque the encapsulating matrix, the greater the shielding effect- and they reconcile findings across different formulations

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The Phase 2 trial reported small increases in heart rate (around 6.7 beats per minute at 12 mg), peaking around week 24 and then declining

Both medications can affect heart rate, and Adderall may elevate blood pressure