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However, the IM route still faces the challenge of BBB penetration and relies on the transport to the CNS after systemic absorption
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It is compatible with the vast majority of research peptides that dissolve readily at neutral or mildly acidic pH including most GLP-1 analogues, amylin analogues, and other water-soluble peptide preparations supplied by Peptides Lab UK
Larger, easier-to-read volume, same dose
Cost and coverage frequently override the efficacy comparison entirely
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