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Pelle MC, Provenzano M, Zaffina I, Pujia R, Giofr F, Luc S, et al
High glucose increases glomerular filtration barrier permeability by activating protein kinase G type I subunits in a Nox4-dependent manner
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That same long duration is why Prozac is often more forgiving if life gets messy and a dose is missed
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