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VP13 Estimating Meaningful Score Differences and Meaningful Score Regions for the PROMIS Pediatric Asthma Impact Scale Jing Yuan 1 , Li Lin 2 , Kevin Weinfurt 2 , Nicole Lucas 2 , Allison Burbank 3 , Michelle Hernandez 3 , I-Chan Huang 4 , Bryce Reeve 1 1 Duke University, Durham, North Carolina, USA, 2 Duke University School of Medicine, Durham, North Carolina, USA, 3 University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA

High Costs: Brand-name GLP-1 medications come at a premium, with prices reaching $1,349 per month in the US compared to significantly lower costs in other countries

These conditions are extremely common, particularly in women, and many patients safely use GLP-1 medications while on thyroid hormone replacement

The physiological or therapeutic significance of GLP-1 RA engagement at these peripheral sites remains unclear and warrants further investigation

By negotiating directly with manufacturers like Novo Nordisk and Eli Lilly , the government has secured a net price that allows for the drastically reduced $50 copay