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The most frequently reported adverse effects of GLP-1 receptor agonists are gastrointestinal in nature, including nausea, vomiting, diarrhea, constipation, and abdominal discomfort
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Patients should seek immediate medical attention for severe, persistent abdominal pain that may radiate to the back, with or without vomiting
Patients should attempt bowel movements at the same time daily, ideally after meals when the gastrocolic reflex naturally stimulates colonic activity
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