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No serious systemic adverse events have been documented in peer-reviewed human studies at therapeutic doses
Additionally, castration considerably decreased the expression of important antioxidant enzymes (AOEs) (GPx1, thioredoxin, SOD2, and peroxiredoxin 5) and markedly increased the expression of ROS-generating NAD(P)H oxidases
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Different ingredients work through different biological pathways, which directly affects their effectiveness, safety, and suitability for various skin types
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