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For now, patients face a clear set of tradeoffs: oral convenience with approximately 15% weight loss (semaglutide or orforglipron), or injectable inconvenience with approximately 20-22% weight loss (tirzepatide)
They were developed toward different endpoints, so any claim that one is better, stronger, or safer than the other is cross-trial inference across unrelated studies, not a measured result
Policy and Global Health Policy advances in 2025 laid critical groundwork for the next phase of obesity care
This is standard across virtually all telehealth GLP-1 providers and reflects the perishable nature of compounded medications that require refrigerated storage
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