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Collectively, IGF2R-directed LYTACs exemplify a versatile and potent nanomaterial strategy for achieving targeted protein degradation, with applications spanning nucleic acid nanostructures, small molecule conjugates, liposomal delivery, and engineered proteins to overcome cancer resistance mechanisms
IGF is mainly produced by the liver, as well as tumor cells and cancer-associated macrophages (Fig
Number of Syringes Required : More extensive treatments that involve larger areas may require additional syringes, raising the overall cost
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