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Dysesthesia, an unpleasant tingling or burning sensation in the skin, affected about 1 in 5 patients on the 12 mg dose and 1 in 13 on the 9 mg dose though Lilly said most cases were mild and rarely caused participants to drop out

(PubMed) Monti DA, Mitchell E, Bazzan AJ, et al

Peroxiredoxin-1 regulates lipid peroxidation in corneal endothelial cells

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Secondly, we probably are the industry's leading harvester of insights from human genetic variation, if you know our work at deCODE Genetics in Iceland