p 30 kg/m 2 ) In a post hoc analysis, patients randomized to Wegovy HD (N=1,005) had a mean baseline BMI of 2 After 72 weeks on Wegovy HD (N=950), along with diet and exercise, 43.2% reached a BMI vs 8.2% of patients on placebo Limitations 2 : This analysis was not prespecified in the study protocol and was not controlled for multiplicity Post hoc analyses are hypothesis generating and clinical validity cannot be determined # Observed data include only patients who had a body-weight assessment at week 72 (950 of 1,005 for Wegovy HD 7.2 mg injection arm and 171 of 201 for placebo arm) and do not include all randomized patients
EMA, 2024)
It acknowledges that the fatigue experienced in Long COVID and ME/CFS is not monolithic
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