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Mintzes B et al

This homeostatic system is aimed at maintaining a stable body weight and requires the existence of a network of signals conveying information from the periphery to the central nervous system (CNS), where these signals are integrated and contribute to long-term and short-term regulation of body weight (Cummings and Schwartz, It is clear that any dysfunction in the pathways involved in maintaining body weight homeostasis may lead to weight gain and obesity

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