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Goldberg AD, Becker LC, Bonsall R, Cohen JD, Ketterer MW, Kaufman PG,

Its tetrapeptide simplicity belies the complexity of the molecular machinery it engages and for researchers willing to interrogate that machinery rigorously, it offers a window into some of the most fundamental questions in biological aging science

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The primary antibodies used were anti- VEGF-A (Santa Cruz Biotechnology, Santa Cruz, CA, USA), anti- VEGFR1 (Cell Signaling Technology, Berkeley, CA, USA), anti- pVEGFR1 (Cell Signaling Technology, Berkeley, CA, USA), anti- AKT (Santa Cruz Biotechnology, Santa Cruz, CA, USA), anti- pAKT (Santa Cruz Biotechnology, Santa Cruz, CA, USA), anti- ERK (Cell Signaling Technology, Berkeley, CA, USA), anti- pERK (Cell SignalingT echnology, Berkeley, CA, USA), anti- p38 (Cell Signaling Technology, Berkeley, CA, USA), anti- p-p38 (Cell Signaling Technology, Berkeley, CA, USA), anti- eNOS (Proteintech, Chicago, IL, USA), anti- p-eNOS (Proteintech, Chicago, IL, USA), anti- CHOP (Cell Signaling Technology, Berkeley, CA, USA) and anti- -actin (Cell Signaling Technology, Berkeley, CA, USA)

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