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Allergic reactions: While rare, it is possible to have an allergic reaction to vitamin B12 injections

When NAD+ levels drop, mitochondrial function suffers, energy production declines, and metabolism slows

Signs You May Have a B12 Deficiency B12 deficiency can cause a variety of symptoms, including fatigue, headaches, depression, pale or yellow skin, mental impairment, and pain and inflammation of the mouth and tongue

No, it is not FDA-approved, and much of the evidence is preclinical

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