Large numbers of activated microglia and reactive astrocytes along with infiltration of inflammatory cells have been observed in the brainstem and spinal cord in both ALS patient and animal models [20, 24, 4653]
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Meaningful weight loss with tolerable side effects and a very low discontinuation rate
Yu Y, Song J, Guo X, Wang S, Yang X, Chen L et al
Less tryptophan for serotonin More quinolinic acid (which upregulates NMDA receptors and anxiety) Increased depressive symptoms in chronic illness This is why so many patients with gut issues, autoimmunity, or Lyme experience mood changes