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Given the vision-threatening concerns and widespread use of GLP-1RAs, some suggest candid patient conversations and closer follow-up may be warranted

Arch Biochem Biophys 237:408414 Cadenas E, Boveris A, Ragan CI, Stoppani AO (1977) Production of superoxide radicals and hydrogen peroxide by NADH-ubiquinone reductase and ubiquinol-cytochrome c reductase from beef-heart mitochondria

At the 8mg dose, participants lost an average of 21.6kg of fat mass compared to placebo

It stands out from other GLP-1 medications because it acts on three hormone pathways at once: GLP-1, GIP, and glucagon