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Preclinical studies in rodent models have consistently demonstrated that GLP-1 agonists decrease alcohol consumption, reduce alcohol-seeking behavior, and prevent relapse-like drinking after periods of abstinence

However, I would suggest that GLP-1s might be a unique case study, potentially not fully representative of the broader pharmaceutical market

Int J Syst Evol Microbiol (2004) 54(Pt 5):146976.10.1099/ijs.0.02873-0 196 EverardABelzerCGeurtsLOuwerkerkJPDruartCBindelsLBet alCross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity

PMID: 32829981

Also, excessive oxidant stress from pollutants can damage DNA and impair sperm function